Ammonium Chloride → 5-Chloro-2-hex-1-enyl-1H-indole

Beteiligte Stoffe

Reaktionsschritte

To the cold suspension of Pentyl-triphenyl-phosphonium bromide in THF was added LiHMDS in THF and the mixture was stirred for 30 minutes. A solution of 5-Chloro-1H-indole-2-carbaldehyde in THF was added to the reaction mixture and stirred for 3 hours. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.

Herkunft & Nachweise