(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine → (S)-5-cyclopentyl-N-(2-(methoxymethyl)pyrrolidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine	HCID 7156993	—
Edukt	5-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid	HCID 71294186	—
Produkt	(S)-5-cyclopentyl-N-(2-(methoxymethyl)pyrrolidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide	HCID 71294153	—

Reaktionsschritte

The title compound was synthesized in analogy to Example 1 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid (example 14c) and (2S)-2-(methoxymethyl)-1-pyrrolidinamine (CAN 59983-39-0) as starting materials; MS (EI) 402.3 (M+H)+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08648099B2
Quelldatensatz	uspto-grants-2014_02
ORD ID	ord-1dfedfafb04f446bb312dfa1068696f8
Quellennotiz	uspto-grants-2014_02