3-Cyano-2-pyridone → 955399-19-6
Reaktionsgleichung
[O:1]=[C:2]1[C:7]([C:8]#[N:9])=[CH:6][CH:5]=[CH:4][NH:3]1.[NH4+]=[S:11]>CO>[O:1]=[C:2]1[C:7]([C:8](=[S:11])[NH2:9])=[CH:6][CH:5]=[CH:4][NH:3]1Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 130 °C
Versuchsvorschrift
To a suspension of 2-oxo-1,2-dihydropyridine-3-carbonitrile (0.211 g) in methanol (14 mL) was added a 40% aqueous solution of ammonium sulfide (0.50 mL). The reaction mixture was heated at 130° C. in a microwave reactor for 2 hours. The reaction mixture was concentrated. The residue obtained was triturated with methanol and the solid filtered to obtain the title compound (0.174 g) having the following physical data.
Aufarbeitung
- concentrationThe reaction mixture was concentrated
- customThe residue obtained
- customwas triturated with methanol
- filtrationthe solid filtered
Quellen und Nachweise
- ORD-Eintrag
- ord-d76337db382d4ab8aaa875a0da4c4660
- Quelldatensatz
- uspto-grants-2014_08
- Patentnummer
- US08809538B2
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