Cyclopropanemethanol → HCID 58504038, Verbindung

Reaktionsgleichung

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6](Cl)[N:5]=[C:4]([C:11]([NH:13][CH2:14][CH:15]2[CH2:20][CH2:19][N:18]([CH2:21][C:22]3[S:26][C:25]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[F:33])=[N:24][CH:23]=3)[CH2:17][CH2:16]2)=[O:12])[CH:3]=1.[CH:34]1([CH2:37][OH:38])[CH2:36][CH2:35]1>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:38][CH2:37][CH:34]2[CH2:36][CH2:35]2)[N:5]=[C:4]([C:11]([NH:13][CH2:14][CH:15]2[CH2:20][CH2:19][N:18]([CH2:21][C:22]3[S:26][C:25]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[F:33])=[N:24][CH:23]=3)[CH2:17][CH2:16]2)=[O:12])[CH:3]=1

Komponenten

Edukt 2

HCID 75644Cyclopropanemethanol

HCID 58503938HCID 58503938, Verbindung

Produkt 1

HCID 58504038HCID 58504038, Verbindung

Versuchsvorschrift

According to the same procedure described in Example 204, using the compound prepared in Example 393 instead of the compound prepared in Example 215 and cyclopropylmethanol instead of 1-cyclopropylethanol, the title compound having the following physical data was obtained.

Quellen und Nachweise

ORD-Eintrag: ord-ca51a781f55c498c8d57f746a3996395
Quelldatensatz: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08809538B2

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