Isopropanol → HCID 58504016, Verbindung

Reaktionsgleichung

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6](Cl)[N:5]=[C:4]([C:11]([NH:13][CH2:14][CH:15]2[CH2:20][CH2:19][N:18]([CH2:21][C:22]3[S:26][C:25]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[F:33])=[N:24][CH:23]=3)[CH2:17][CH2:16]2)=[O:12])[CH:3]=1.[CH:34]([OH:37])([CH3:36])[CH3:35]>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:37][CH:34]([CH3:36])[CH3:35])[N:5]=[C:4]([C:11]([NH:13][CH2:14][CH:15]2[CH2:20][CH2:19][N:18]([CH2:21][C:22]3[S:26][C:25]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[F:33])=[N:24][CH:23]=3)[CH2:17][CH2:16]2)=[O:12])[CH:3]=1

Komponenten

Edukt 2

HCID 3776Isopropanol

HCID 58503938HCID 58503938, Verbindung

Produkt 1

HCID 58504016HCID 58504016, Verbindung

Versuchsvorschrift

According to the same procedure described in Example 204, using the compound prepared in Example 393 instead of the compound prepared in Example 215 and isopropanol instead of 1-cyclopropylethanol, the title compound having the following physical data was obtained.

Quellen und Nachweise

ORD-Eintrag: ord-d629a47f602c43b78ccc74f94ed30afa
Quelldatensatz: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08809538B2

Notizen zur Reaktion

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