Hydrochloric Acid → HCID 58028470, Verbindung

HRID 2408313Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2408313
[O:1]1CCO[CH:2]1[C:6]1[CH:7]=[C:8]([N:12]([C:50]2[C:59]3[C:54](=[CH:55][CH:56]=[CH:57][CH:58]=3)[CH:53]=[CH:52][CH:51]=2)[C:13]2[CH:25]=[CH:24][C:23]3[C:22]4[C:17](=[CH:18][C:19]([N:26]([C:37]5[CH:42]=[CH:41][CH:40]=[C:39]([CH:43]6OCC[O:44]6)[CH:38]=5)[C:27]5[C:36]6[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=6)[CH:30]=[CH:29][CH:28]=5)=[CH:20][CH:21]=4)[C:16]([CH3:49])([CH3:48])[C:15]=3[CH:14]=2)[CH:9]=[CH:10][CH:11]=1.Cl>CC(C)=O>[CH3:48][C:16]1([CH3:49])[C:17]2[CH:18]=[C:19]([N:26]([C:37]3[CH:38]=[C:39]([CH:40]=[CH:41][CH:42]=3)[CH:43]=[O:44])[C:27]3[C:36]4[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=4)[CH:30]=[CH:29][CH:28]=3)[CH:20]=[CH:21][C:22]=2[C:23]2[C:15]1=[CH:14][C:13]([N:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH:2]=[O:1])[C:50]1[C:59]3[C:54](=[CH:55][CH:56]=[CH:57][CH:58]=3)[CH:53]=[CH:52][CH:51]=1)=[CH:25][CH:24]=2

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 58028464N2,N7-bis(3-(1,3-dioxolan-2-yl)phenyl)-9,9-dimethyl-N2,N7-di(naphthalen-1-yl)-9H-fluorene-2,7-diamine

Produkt 1

HCID 58028470HCID 58028470, VerbindungAusbeute 97,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a three-neck round-bottom flask, were added 8.0 g N2,N7-bis(3-(1,3-dioxolan-2-yl)phenyl)-9,9-dimethyl-N2,N7-di(naphthalen-1-yl)-9H-fluorene-2,7-diamine and in 100 mL acetone. 41.1 mL 2 M hydrochloric acid solution was added slowly to the reaction mixture through an addition funnel. After TLC showed the reaction was done, the solvent was removed by evaporation. 200 mL Ethyl acetate was added, and the reaction mixture was extracted using DI water (4×200 mL). The organic layer was dried over sodium sulfate. After filtration, the solvent was removed by evaporation. The product (6.9 g) was obtained after drying under vacuum, and was carried on to next step without further purification. The structure was confirmed by NMR.

Aufarbeitung

  1. customthe solvent was removed by evaporation
  2. addition200 mL Ethyl acetate was added
  3. extractionthe reaction mixture was extracted
  4. dry with materialThe organic layer was dried over sodium sulfate
  5. filtrationAfter filtration
  6. customthe solvent was removed by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-b5001a5d5ac24e8cabf07e41d1310ce2
Quelldatensatz
uspto-grants-2014_08
Patentnummer
US08815639B2

Notizen zur Reaktion

Wird geladen…