4-Methyloxybenzyl chloride → 5-Isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione

Reaktionsgleichung

[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[NH:6][C:5]1=[O:10])([CH3:3])[CH3:2].[CH3:11][O:12][C:13]1[CH:20]=[CH:19][C:16]([CH2:17]Cl)=[CH:15][CH:14]=1>>[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[N:6]([CH2:17][C:16]2[CH:19]=[CH:20][C:13]([O:12][CH3:11])=[CH:14][CH:15]=2)[C:5]1=[O:10])([CH3:3])[CH3:2]

Komponenten

Edukt 2

HCID 699934-Methyloxybenzyl chloride

HCID 1030335-Isopropylhydantoin

Produkt 1

HCID 712528645-Isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione

Versuchsvorschrift

Using 5-isopropylimidazolidine-2,4-dione (2.00 g) and 4-methoxybenzyl chloride (2.29 mL) and by the reaction and treatment in the same manner as in Preparation Example 51, the title compound (2.72 g) was obtained.

Aufarbeitung

customby the reaction and treatment in the same manner
customas in Preparation Example 51

Quellen und Nachweise

ORD-Eintrag: ord-189474c7e3ac4500bdba415a95c91613
Quelldatensatz: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08816079B2

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