3,5-Dimethyl-2,4-Imidazolidinedione → Methyl 6-(3,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-methylnicotinate
Reaktionsgleichung
Br[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[C:4]([CH3:12])[N:3]=1.[CH3:13][N:14]1[C:18](=[O:19])[CH:17]([CH3:20])[NH:16][C:15]1=[O:21]>>[CH3:13][N:14]1[C:18](=[O:19])[CH:17]([CH3:20])[N:16]([C:2]2[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[C:4]([CH3:12])[N:3]=2)[C:15]1=[O:21]Komponenten
3
Versuchsvorschrift
Using methyl 6-bromo-2-methylnicotinate (96 mg) and 3,5-dimethylimidazolidine-2,4-dione (107 mg) described in Preparation Example 217 and by the reaction and treatment in the same manner as in Preparation Example 48, the title compound (19 mg) was obtained.
Aufarbeitung
- customdescribed in Preparation Example 217 and by the reaction and treatment in the same manner as in Preparation Example 48