[4-(5-Ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone → HCID 71252895, Verbindung

HRID 2411453Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2411453
[CH3:1][CH:2]1[CH2:6][S:5](=[O:8])(=[O:7])[NH:4][CH2:3]1.[CH2:9]([C:11]1[CH:12]=[C:13]([CH3:32])[C:14]([N:17]2[CH2:22][CH2:21][N:20]([C:23]([C:25]3[CH:30]=[CH:29][C:28](I)=[CH:27][CH:26]=3)=[O:24])[CH2:19][CH2:18]2)=[N:15][CH:16]=1)[CH3:10]>>[CH2:9]([C:11]1[CH:12]=[C:13]([CH3:32])[C:14]([N:17]2[CH2:18][CH2:19][N:20]([C:23]([C:25]3[CH:30]=[CH:29][C:28]([N:4]4[CH2:3][CH:2]([CH3:1])[CH2:6][S:5]4(=[O:8])=[O:7])=[CH:27][CH:26]=3)=[O:24])[CH2:21][CH2:22]2)=[N:15][CH:16]=1)[CH3:10]

Komponenten

3

Edukt 2

HCID 58484605[4-(5-Ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanoneHCID 59155177ZJNXUAJQNBXKSL-UHFFFAOYSA-N

Produkt 1

HCID 71252895HCID 71252895, VerbindungAusbeute 9 %

Versuchsvorschrift

Using 4-methylisothiazolidine 1,1-dioxide (202 mg) described in Preparation Example 9 and [4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (500 mg) described in Preparation Example 133 and by the reaction and treatment in the same manner as in Example 1, the title compound (46 mg) was obtained.

Aufarbeitung

  1. customdescribed in Preparation Example 133 and by the reaction and treatment in the same manner as in Example 1

Quellen und Nachweise

ORD-Eintrag
ord-f68693dfeaf54c47932c25b328cdc3ba
Quelldatensatz
uspto-grants-2014_08
Patentnummer
US08816079B2

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