Benzenesulfonyl chloride → 2-Methoxy-3-octadecyloxy-1-propanol benzene-sulfonate

HRID 2412384

Reaktionsgleichung

Reaktionsgleichung von HRID 2412384
COC(COCCCCCCCCCCCCCCCCCC)CS.[CH3:26][O:27][CH:28]([CH2:31][O:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])[CH2:29][OH:30].[CH:51]1[CH:56]=[CH:55][C:54]([S:57](Cl)(=[O:59])=[O:58])=[CH:53][CH:52]=1>N1C=CC=CC=1>[C:54]1([S:57]([O:30][CH2:29][CH:28]([O:27][CH3:26])[CH2:31][O:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])(=[O:59])=[O:58])[CH:55]=[CH:56][CH:51]=[CH:52][CH:53]=1

Komponenten

5

Edukt 3

HCID 7369Benzenesulfonyl chlorideHCID 3364221-Propanol, 2-methoxy-3-(octadecyloxy)-HCID 204322112-Methoxy-3-octadecyloxy-1-propanethiol

Produkt 1

HCID 204322202-Methoxy-3-octadecyloxy-1-propanol benzene-sulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

The 2-methoxy-3-octadecyloxy-1-propanethiol used as starting material is prepared in the following manner: 2-methoxy-3-octadecyloxy-1-propanol is reacted with benzenesulfochloride in anhydrous pyridine to give 2-methoxy-3-octadecyloxy-1-propanol benzene-sulfonate, (oil). This is then reacted with thiorea in butanol to give the isothiuronium salt which is saponified with potassium hydroxide solution and the thiol liberated with hydrochloric acid.

Aufarbeitung

  1. customis prepared in the following manner

Quellen und Nachweise

ORD-Eintrag
ord-d30426eed12a43af96a546584e943e86
Quelldatensatz
uspto-grants-1985_01
Patentnummer
US04492659

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