Chloroacetonitrile → [(3,4-Dichlorophenyl)sulfanyl]acetonitrile

HRID 2413332

Reaktionsgleichung

Reaktionsgleichung von HRID 2413332
Cl[CH2:2][C:3]#[N:4].[Cl:5][C:6]1[CH:7]=[C:8]([S:13][Si](C)(C)C)[CH:9]=[CH:10][C:11]=1[Cl:12]>C(#N)C.CN(C)P(=O)(N(C)C)N(C)C>[Cl:5][C:6]1[CH:7]=[C:8]([S:13][CH2:2][C:3]#[N:4])[CH:9]=[CH:10][C:11]=1[Cl:12]

Komponenten

5

Edukt 2

HCID 7856ChloroacetonitrileHCID 20491069[(3,4-Dichlorophenyl)sulfanyl](trimethyl)silane

Produkt 1

HCID 18542995[(3,4-Dichlorophenyl)sulfanyl]acetonitrileAusbeute 96,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6342AcetonitrileLösungsmittelHCID 12679HexamethylphosphoramideLösungsmittel

Versuchsvorschrift

3.5 ml (55 mmoles) of chloroacetonitrile were added to a refluxing solution of 11.0 g (44 mmoles) of 3,4-dichlorophenylthio(trimethyl)silane in a mixture of 25 ml of acetonitrile and 10 ml of hexamethylphosphoric triamide and the reaction was complete with 2 minutes. The residue obtained after evaporation of the acetonitrile was dissolved in ethyl acetate, and the solution was washed with water, dried and evaporated to dryness to obtain 9.30 g (93% yield) of (3,4-dichlorophenylthio)acetonitrile boiling at 127°-130° C./0.4 mm Hg and having a refractive index of nD25 =1.5920.

Aufarbeitung

  1. customThe residue obtained
  2. customafter evaporation of the acetonitrile
  3. dissolutionwas dissolved in ethyl acetate
  4. washthe solution was washed with water
  5. customdried
  6. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-16346bd1c6314838abc2eabb84ef2837
Quelldatensatz
uspto-grants-1985_01
Patentnummer
US04496720

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