HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tris(hydroxymethyl)aminomethane → 2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tris(hydroxymethyl)aminomethane | HCID 6503 | — |
| Edukt | 6-Chrysenecarbaldehyde | HCID 12438774 | — |
| Edukt | 2-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride | HCID 13375278 | — |
| Lösungsmittel | Diethyl ether methanol | HCID 21864698 | — |
| Produkt | 2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride | HCID 13375340 | — |
Reaktionsschritte
Using the reductive amination procedure described in 1B, 6-chrysenecarbaldehyde (1A) and tris(hydroxymethyl)aminomethane (Aldrich) gave 2-((6-chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride, mp 238°-239° (dec), (CH3OH/Et2O), (C, H, Cl, N).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04719046 |
| Quelldatensatz | uspto-grants-1988_01 |
| ORD ID | ord-7e3ad97cfbb0440ebf7314655bb90a2f |
| Quellennotiz | uspto-grants-1988_01 |