HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,1'-Carbonyldiimidazole → N-{3-Chloro-4-[4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidin-1-yl]phenyl}-1-cyanocyclopropanecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Edukt | 1-Cyanocyclopropanecarboxylic acid | HCID 2733259 | — |
| Edukt | 1-[1-(4-Amino-2-chlorophenyl)piperidin-4-yl]-1,4-dihydro-2H-3,1-benzoxazin-2-one | HCID 22644680 | — |
| Produkt | N-{3-Chloro-4-[4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidin-1-yl]phenyl}-1-cyanocyclopropanecarboxamide | HCID 22644647 | — |
Reaktionsschritte
The title compound was prepared from the product of example 120 step (ii) (0.05 g), carbonyldiimidazole (0.025 g) and 1-cyano-1-cyclopropane carboxylic acid (0.019 g) using the method of example 115 step (i). Yield 0.003 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06812226B2 |
| Quelldatensatz | uspto-grants-2004_11 |
| ORD ID | ord-656ec2424c1c453d9bfa60cbcd1e00ee |
| Quellennotiz | uspto-grants-2004_11 |