8-OH-Dpat → 6,7,8,9-Tetrahydro-8-(1-piperidinyl)-naphtho[1,2-b]furan
Reaktionsgleichung
[CH2:1]([N:4]([CH2:16][CH2:17][CH3:18])[CH:5]1[CH2:14][C:13]2[C:12]([OH:15])=[CH:11][CH:10]=[CH:9][C:8]=2[CH2:7][CH2:6]1)[CH2:2]C.N1(C2CC3C(O)=CC=CC=3CC2)CCC[CH2:21][CH2:20]1>>[N:4]1([CH:5]2[CH2:14][C:13]3[C:12]4[O:15][CH:20]=[CH:21][C:11]=4[CH:10]=[CH:9][C:8]=3[CH2:7][CH2:6]2)[CH2:1][CH2:2][CH2:18][CH2:17][CH2:16]1Komponenten
3
Versuchsvorschrift
In the same manner but replacing 5,6,7,8-tetrahydro-7-(dipropylamino)-1-naphthalenol with an equivalent amount of 5,6,7,8-tetrahydro-7-(1-piperidinyl)-1-naphthalenol, 6,7,8,9-tetrahydro-8-(1-piperidinyl)-naphtho[1,2-b]furan is obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-592317e72fef48099901ed47434ce8c6
- Quelldatensatz
- uspto-grants-1984_09
- Patentnummer
- US04470990