p-Chlorothiophenol → HCID 23693160, Verbindung

HRID 2418333Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2418333
[OH-].[K+:2].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([SH:10])=[CH:6][CH:5]=1>CO>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([S-:10])=[CH:6][CH:5]=1.[K+:2]

Komponenten

4

Edukt 2

HCID 7815p-ChlorothiophenolHCID 14797Potassium Hydroxide

Produkt 1

HCID 23693160HCID 23693160, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

To a solution of potassium hydroxide (2.5 g.) in methanol (30 ml.) was dissolved 4-chlorobenzenethiol (6.5 g.), and methanol was distilled off to give potassium 4-chlorobenzenethiolate. To this product were added ethyl 2-(2-nitro-3-chlorophenyl)acetate (10 g.) and dimethylformamide (50 ml.) and stirred for 1.5 hours at 100° C. The reaction mixture was poured into water (300 ml.) and extracted with diethyl ether. The extract was washed with water, dried over magnesium sulfate and then evaporated under reduced pressure. The residue was recrystallized from a mixture of benzene and n-hexane to give yellow needles of the captioned compound (9.9 g.). mp 77° to 79° C.

Aufarbeitung

  1. distillationwas distilled off

Quellen und Nachweise

ORD-Eintrag
ord-a11aed851c7b4ca3851e97ab0fcdc7b8
Quelldatensatz
uspto-grants-1984_09
Patentnummer
US04472433

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