Sodium Hydroxide → HCID 178424782, Verbindung

Reaktionsgleichung

[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:3]=1[CH:4]=O.I.[NH2:12][NH:13][C:14]([NH:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[NH:15].[OH-].[Na+]>C(O)C>[CH2:17]([NH:16][C:14]([NH:13][N:12]=[CH:4][C:3]1[C:2]([CH3:1])=[CH:9][CH:8]=[CH:7][C:6]=1[CH3:10])=[NH:15])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Komponenten

Versuchsvorschrift

A solution of 1.34 g. of 2,6-dimethylbenzaldehyde [G. Lock and K. Schmidt, J. Prakt. Chem., 140, 229 (1934) and 2.92 g. of 1-amino-3-benzylguanidine hydroiodide in 25 ml. of absolute ethanol is heated at reflux for 18 hours. The solution is evaporated under reduced pressure to give a syrup which is made alkaline with aqueous NaOH. The mixture is extracted with chloroform. The chloroform extract is evaporated under reduced pressure to give a yellow syrup. Trituration of this syrup with diethyl ether and n-hexane, followed by filtration, gives the desired product as light pink crystals, m.p. 125°-126° C.