L-Alanine → Leucyl-alanyl-glycyl-valine
Reaktionsgleichung
[NH2:1][C@H:2]([C:7]([OH:9])=O)[CH2:3][CH:4]([CH3:6])[CH3:5].[NH2:10][C@H:11]([C:13]([OH:15])=O)[CH3:12].[NH2:16][C@H:17]([C:21]([OH:23])=[O:22])[CH:18]([CH3:20])[CH3:19]>>[NH2:1][C@H:2]([C:7]([NH:10][C@H:11]([C:13]([NH:1][CH2:2][C:7]([NH:16][C@H:17]([C:21]([OH:23])=[O:22])[CH:18]([CH3:20])[CH3:19])=[O:9])=[O:15])[CH3:12])=[O:9])[CH2:3][CH:4]([CH3:5])[CH3:6]Komponenten
4
Versuchsvorschrift
The completed Boc-tetrapeptide resin was subjected to steps (1) and (2) to cleave the Boc group and worked up as described for (A) to yield 707 mg of peptide resin. Amino acid analysis: Gly 1.05, Ala 1.00, Val 1.12, Leu 1.05.
Quellen und Nachweise
- ORD-Eintrag
- ord-2f0d1be5949d48eea239a4bd8cbc9854
- Quelldatensatz
- uspto-grants-1978_08