Hydrochloric Acid → HCID 20313024, Verbindung

HRID 2420109Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2420109
[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([OH:16])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH2:18](O)[CH3:19]>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([O:16][CH2:18][CH3:19])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 30428422-Pyridinecarboxylic acid, 5-(phenylmethyl)-

Produkt 1

HCID 20313024HCID 20313024, Verbindung

Versuchsvorschrift

2.0 Grams of 5-benzylpicolinic acid were suspended in 25 ml. of ethanol. The resulting suspension was saturated with hydrogen chloride gas under ice-cooling. After reflux for three hours, the reaction solution was concentrated under reduced pressure. Ether was added thereto to form crystals. The crystals were then recrystallized from a solvent comprising a mixture of acetone/ether to obtain 1.7 g of ethyl 5-benzylpicolinate of a melting point of 109°~111° C.

Aufarbeitung

  1. temperaturecooling
  2. temperatureAfter reflux for three hours
  3. concentrationthe reaction solution was concentrated under reduced pressure
  4. additionEther was added
  5. customto form crystals
  6. customThe crystals were then recrystallized from a solvent comprising
  7. additiona mixture of acetone/ether

Quellen und Nachweise

ORD-Eintrag
ord-60ae81fb857d426eba9005aab5bb7eeb
Quelldatensatz
uspto-grants-1978_08
Patentnummer
US04109000

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