HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(p-Chlorophenyl)cyclobutanecarboxylic acid → 2-({1-[1-(4-Chlorophenyl)cyclobutyl]-4,4-dimethyl-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(p-Chlorophenyl)cyclobutanecarboxylic acid | HCID 602761 | — |
| Edukt | 2-(4-Methoxyphenyl)-2-methylpropan-1-amine | HCID 3581364 | — |
| Edukt | 1-(4-Fluorophenyl)cyclobutanecarboxylic acid | HCID 16769017 | — |
| Edukt | 2-({1-[1-(4-Fluorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine | HCID 58246324 | — |
| Produkt | 2-({1-[1-(4-Chlorophenyl)cyclobutyl]-4,4-dimethyl-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine | HCID 58246302 | — |
Reaktionsschritte
2-({1-[1-(4-Chlorophenyl)cyclobutyl]-4,4-dimethyl-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine was prepared analogously to 2-({1-[1-(4-fluorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine (cf. example 65) using 2-(4-methoxyphenyl)-2-methylpropan-1-amine and 1-(4-chlorophenyl)cyclobutanecarboxylic acid in place of 2-(4-methoxyphenyl)ethanamine and 1-(4-fluorophenyl)cyclobutanecarboxylic acid, respectively.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08653100B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-89f8d178c1b24bb4a5071f72c287e11a |
| Quellennotiz | uspto-grants-2014_02 |