1-Hydroxybenzotriazole, ammonium salt → 3-(4-((2'-(Aminocarbonyl)biphenyl-3-yl)methoxy)phenyl)propanoic acid
Reaktionsgleichung
C([O:5][C:6]([CH2:8][CH2:9][C:10]1[CH:32]=[CH:31][C:13]([O:14][CH2:15][C:16]2[CH:17]=[C:18]([C:22]3[C:23]([C:28](O)=[O:29])=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:19]=[CH:20][CH:21]=2)=[CH:12][CH:11]=1)=[O:7])(C)(C)C.[NH4+].O[N:35]1C2C=CC=CC=2N=N1>>[NH2:35][C:28]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=1[C:18]1[CH:19]=[CH:20][CH:21]=[C:16]([CH2:15][O:14][C:13]2[CH:31]=[CH:32][C:10]([CH2:9][CH2:8][C:6]([OH:5])=[O:7])=[CH:11][CH:12]=2)[CH:17]=1)=[O:29]Komponenten
3
Versuchsvorschrift
The title compound was synthesized in the same manner as in Example 285 from 3′-[4-(2-tert-butoxycarbonylethyl)phenoxymethyl]biphenyl-2-carboxylic acid and 1-hydroxybenzotriazole ammonium salt. colorless crystals (yield 66%). MS (APCI−): 374 (M−H).
Quellen und Nachweise
- ORD-Eintrag
- ord-7cbd2a406f344ab38e2a83c68be1da89
- Quelldatensatz
- uspto-grants-2011_06