HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → 3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | 3-Aminopicolinic acid | HCID 73836 | — |
| Edukt | 4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde | HCID 7379340 | — |
| Produkt | 3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-one | HCID 11494881 | — |
Reaktionsschritte
The entitled compound was obtained according to the method of Example 15 but starting from 3-aminopyridin-2-carboxylic acid, methylamine and 4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde. The resulting compound was recrystallized from diethyl ether-heptane to give a colorless acicular crystal (m.p. 83.5-88.5° C.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07960394B2 |
| Quelldatensatz | uspto-grants-2011_06 |
| ORD ID | ord-26b370b5224e4669b1e0f2ab18ea402c |
| Quellennotiz | uspto-grants-2011_06 |