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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2422622Erstellt: 27. Oktober 2026

Methylamine → 3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-one

https://huagongshe.com/reaction/2422622

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethylamineHCID 6329—
Edukt3-Aminopicolinic acidHCID 73836—
Edukt4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehydeHCID 7379340—
Produkt3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-oneHCID 11494881—

Reaktionsschritte

The entitled compound was obtained according to the method of Example 15 but starting from 3-aminopyridin-2-carboxylic acid, methylamine and 4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde. The resulting compound was recrystallized from diethyl ether-heptane to give a colorless acicular crystal (m.p. 83.5-88.5° C.).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07960394B2
Quelldatensatzuspto-grants-2011_06
ORD IDord-26b370b5224e4669b1e0f2ab18ea402c
Quellennotizuspto-grants-2011_06