3-Chloroaniline → N-(Benzimidazol-2-yl)-3-chloroaniline

Reaktionsgleichung

Cl[C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[Cl:11][C:12]1[CH:13]=[C:14]([CH:16]=[CH:17][CH:18]=1)[NH2:15]>>[N:6]1[C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[NH:3][C:2]=1[NH:15][C:14]1[CH:16]=[CH:17][CH:18]=[C:12]([Cl:11])[CH:13]=1

Komponenten

Edukt 2

HCID 79323-Chloroaniline

HCID 785722-Chlorobenzimidazole

Produkt 1

HCID 923992N-(Benzimidazol-2-yl)-3-chloroaniline

Versuchsvorschrift

The title compound was prepared from 2-chlorobenzimidazole and 3-chloroaniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 252-257° C.). MS(ES+) m/z 244 ([M+1]+, 100).

Aufarbeitung

customThe product was isolated by filtration

Quellen und Nachweise

ORD-Eintrag: ord-1aabc3b9694d4d4ab1e1c52effea4316
Quelldatensatz: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07960561B2

Notizen zur Reaktion

Wird geladen…