Tetracaine → HCID 86603141, Verbindung
Reaktionsgleichung
[CH3:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]([O:14][CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])=[O:13])=[CH:10][CH:11]=1.[OH:20][P:21]([O-:24])([OH:23])=[O:22].[OH:25][P:26]([O-:29])([O-:28])=[O:27].[Na+].[Na+].[Na+].[Cl-].[Cl-].[K+].[K+]>>[CH3:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([O:14][CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])=[O:13])=[CH:8][CH:7]=1.[CH:11]1([O:27][P:26]([OH:29])([OH:28])=[O:25])[CH:10]([O:22][P:21]([OH:24])([OH:23])=[O:20])[CH:9]([O:27][P:26]([OH:29])([OH:28])=[O:25])[CH:8]([O:22][P:21]([OH:24])([OH:23])=[O:20])[CH:7]([O:27][P:26]([OH:29])([OH:28])=[O:25])[CH:6]1[O:22][P:21]([OH:24])([OH:23])=[O:20]Komponenten
3
Versuchsvorschrift
The film thus obtained is melted and compression molded at 80° C. to give a film about 0.5 mm thick. The film is incubated in phosphate buffered saline (containing 0.02% sodium azide) at pH 7.4 and 37° C., and the buffer solution is assayed periodically by UV to determine the amount of tetracaine released.
Aufarbeitung
- customThe film thus obtained
- custommolded at 80° C.
- customto give a film about 0.5 mm thick