2-Methoxyphenylboronic acid → [1,1'-Biphenyl]-4-sulfonamide, N-(5-hydroxypentyl)-2'-methoxy-
Reaktionsgleichung
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14](Br)=[CH:13][CH:12]=1)(=[O:10])=[O:9].[CH3:18][O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1B(O)O>>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[O:19][CH3:18])=[CH:13][CH:12]=1)(=[O:10])=[O:9]Komponenten
3
Versuchsvorschrift
Using a method analogous to that described in Example 40, 4-bromophenyl-sulfonic acid-(5-hydroxypentyl)-amide and 2-methoxyphenyl boronic acid were reacted to give the title compound as a clear oil. δC (DMSO, 62.9 MHz): 22.7, 29.0, 32.0, 42.7, 55.6, 60.6, 115.5, 121.4, 125.3, 126.1, 128.2, 129.8, 130.2, 138.8, 142.1 and 156.1.
Aufarbeitung
- customwere reacted