Potassium Hydroxide → HCID 67147433, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[N:8]([CH2:14][CH2:15][C:16]([O:18]C)=[O:17])[CH:7]=[C:6]2[C:20]1[N:28](S(C2C=CC(C)=CC=2)(=O)=O)[C:23]2=[N:24][CH:25]=[CH:26][CH:27]=[C:22]2[CH:21]=1.[OH-].[K+]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[N:8]([CH2:14][CH2:15][C:16]([OH:18])=[O:17])[CH:7]=[C:6]2[C:20]1[NH:28][C:23]2=[N:24][CH:25]=[CH:26][CH:27]=[C:22]2[CH:21]=1Komponenten
3
Versuchsvorschrift
3-[5,6-Dimethoxy-3-(1H-pyrrolo[2,3-b]pyridine-2-yl)indol-1-yl]propionic acid is prepared by following the procedure described in example 88a, but using 1 g of methyl 3-[5,6-dimethoxy-3-(1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)indol-1-yl]propionate and a solution of 74 ml of methanolic potassium hydroxide (0.1 g/ml; 1.78M). 0.601 g of 3-[5,6-dimethoxy-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)indol-1-yl]propionic acid is obtained, the characteristics of which are as follows:
Aufarbeitung
- custom3-[5,6-Dimethoxy-3-(1H-pyrrolo[2,3-b]pyridine-2-yl)indol-1-yl]propionic acid is prepared