Hydrochloric Acid → 3-[(Pyrrolidin-1-yl)methyl]benzoic acid--hydrogen chloride (1/1)

HRID 2427243

Reaktionsgleichung

Reaktionsgleichung von HRID 2427243
C[O:2][C:3](=[O:16])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][N:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)[CH:5]=1.[ClH:17]>>[ClH:17].[N:11]1([CH2:10][C:6]2[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=2)[C:3]([OH:16])=[O:2])[CH2:15][CH2:14][CH2:13][CH2:12]1

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 53429637Methyl 3-(pyrrolidin-1-ylmethyl)benzoate

Produkt 1

HCID 185258743-[(Pyrrolidin-1-yl)methyl]benzoic acid--hydrogen chloride (1/1)

Versuchsvorschrift

A solution of 3-pyrrolidin-1-ylmethyl-benzoic acid methyl ester (800 mg, 3.6 mmol) in aqueous 25% hydrochloric acid (15 mL) was stirred at 90° C. for 4 hours. The solvent was evaporated affording the title compound as brown oil (quantitative) that was used as such for the next step.

Aufarbeitung

  1. customThe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-8cda23d7871149ac9cf399e9f52cbf07
Quelldatensatz
uspto-grants-2011_06
Patentnummer
US07968583B2

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