HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl 4-(chlorocarbonyl)benzoate → 5-(4-Methoxycarbonylbenzamido)-2-oxindole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl 4-(chlorocarbonyl)benzoate | HCID 81850 | — |
| Edukt | 5-Amino-2-oxindole | HCID 2773213 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 5-(4-Methoxycarbonylbenzamido)-2-oxindole | HCID 23289962 | 81% |
Reaktionsschritte
A mixture of 82.0 mg 5-amino-2-oxindole and 131.0 mg 4-methoxycarbonylbenzoyl chloride in pyridine was stirred at room temperature for 3 hr and poured into ice water. The precipitate was filtered, washed with water and dried in a vacuum oven to give 138.0 mg of 5-(4-methoxycarbonylbenzamido)-2oxindole (81% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06855730B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-1c489b6e3bdf42119d09d797f8064076 |
| Quellennotiz | uspto-grants-2005_02 |