2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-3-methyl-quinoxaline → HCID 178432135, Verbindung
Reaktionsgleichung
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][N:2]1[C:9]1[C:18]([CH3:19])=[N:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[N:20]1[N:21]=[C:22]([C:25]2[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=2[C:27](O)=[O:28])[NH:23][CH:24]=1>>[CH3:19][C:18]1[C:9]([N:2]2[CH2:3][CH:4]3[CH:5]([CH2:6][N:7]([C:27]([C:26]4[CH:30]=[CH:31][CH:32]=[CH:33][C:25]=4[C:22]4[NH:23][CH:24]=[N:20][N:21]=4)=[O:28])[CH2:8]3)[CH2:1]2)=[N:10][C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:17]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 29 and 2-(4H-[1,2,4]triazol-3-yl)-benzoic acid. MS (ESI) mass calcd. for C24H23N7O, 425.49; m/z found, 426.3 [M+H]+. 1H NMR (CDCl3): 8.13 (d, J=7.3 Hz, 1H), 8.01 (s, 1H), 7.83 (dd, J=8.2, 1.1 Hz, 1H), 7.72 (dd, J=8.3, 1.0 Hz, 1H), 7.59-7.35 (m, 5H), 4.00-3.65 (m, 5H), 3.47 (s, 2H), 3.22-2.89 (m, 3H), 2.70 (s, 3H).
Quellen und Nachweise
- ORD-Eintrag
- ord-34662c7f9d614dc886171a06852e384c
- Quelldatensatz
- uspto-grants-2014_02
- DOI