5-Fluoro-2-(pyrimidin-2-yl)benzoic acid → (5-Fluoro-2-pyrimidin-2-yl-phenyl)-[5-(6-methyl-2-trifluoromethyl-pyrimidin-4-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5-Fluoro-2-(pyrimidin-2-yl)benzoic acid	HCID 67086950	—
Edukt	2-(6-Methyl-2-trifluoromethyl-pyrimidin-4-yl)-octahydro-pyrrolo[3,4-c]pyrrole	HCID 67116308	—
Produkt	(5-Fluoro-2-pyrimidin-2-yl-phenyl)-[5-(6-methyl-2-trifluoromethyl-pyrimidin-4-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone	HCID 69939310	—

Reaktionsschritte

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 13 and Intermediate 31. MS (ESI): mass calculated for C23H20F4N6O, 472.45; m/z found 473.2 [M+H]+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08653263B2
Quelldatensatz	uspto-grants-2014_02
ORD ID	ord-293d5452ae8f4fe6b0de0359c460218a
Quellennotiz	uspto-grants-2014_02