2,4,6-Trimethoxybenzaldehyde → 4-(3-(2,4,6-Trimethoxyphenyl)propyl)benzene-1,3-diol

HRID 245590Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 245590
COC1C=C(C[CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=2[OH:21])C=C(OC)C=1.[CH3:22][O:23][C:24]1[CH:31]=[C:30]([O:32][CH3:33])[CH:29]=[C:28]([O:34][CH3:35])[C:25]=1[CH:26]=O>>[CH3:22][O:23][C:24]1[CH:31]=[C:30]([O:32][CH3:33])[CH:29]=[C:28]([O:34][CH3:35])[C:25]=1[CH2:26][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[OH:21]

Komponenten

3

Edukt 2

HCID 700192,4,6-TrimethoxybenzaldehydeHCID 446117114-(3-(3,5-Dimethoxyphenyl)propyl)benzene-1,3-diol

Produkt 1

HCID 446118434-(3-(2,4,6-Trimethoxyphenyl)propyl)benzene-1,3-diol

Versuchsvorschrift

Compound 31 was synthesized following a similar procedure as described for compound 28 above using as starting materials 2,4-dibenzyloxyacetophenone and 2,4,6-trimethoxybenzaldehyde. 1H-NMR (MeOD, 500 MHz): δ 6.822 (d, 1H, J=8.0 Hz), 6.250 (d, 1H, J=2.5 Hz), 6.197 (dd, 1H, J=2.5 & 8.0 Hz), 6.165 (s, 2H), 3.768 (s, 3H), 3.764 (s, 6H), 2.562 (t, 2H, J=7.5 Hz), 2.461 (t, 2H, J=7.5 Hz), 1.617-1.653 (m, 2H). 13C-NMR (MeOD, 125 MHz): δ 159.273 (C), 158.729 (2C), 155.556 (C), 155.449 (C), 129.655 (2CH), 120.426 (C), 111.382 (C), 105.789 (CH), 101.968 (CH), 90.285 (CH), 54.655 (2CH3), 54.274 (CH3), 29.716 (CH2), 29.064 (CH2), 22.142 (CH2).

Quellen und Nachweise

ORD-Eintrag
ord-d957cedbb1854089aefea1c7ab67ccc6
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08658838B2

Notizen zur Reaktion

Wird geladen…