HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2-BOC-aminophenyl)boronic acid → N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (2-BOC-aminophenyl)boronic acid | HCID 2773226 | — |
| Edukt | N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester | HCID 54284267 | — |
| Produkt | N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester | HCID 54237195 | 73,5% |
Reaktionsschritte
2-(tert-Butoxycarbonylamino)benzeneboronic acid (0.3 g) was coupled with N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester (270 mg) by a similar procedure as described in Examples 15 to give 250 mg of N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester. ESMS: m/z 543 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06855843B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-9e9e7ed7d7784aeeb6a0a3f6851d529b |
| Quellennotiz | uspto-grants-2005_02 |