Ammonia → 8-Hydroxy-2-methyl-7-quinolinecarboxamide

HRID 247257

Reaktionsgleichung

Reaktionsgleichung von HRID 247257
C[O:2][C:3]([C:5]1[C:14]([OH:15])=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([CH3:16])=[N:12]2)=[CH:7][CH:6]=1)=O.[NH3:17]>>[OH:15][C:14]1[C:5]([C:3]([NH2:17])=[O:2])=[CH:6][CH:7]=[C:8]2[C:13]=1[N:12]=[C:11]([CH3:16])[CH:10]=[CH:9]2

Komponenten

3

Edukt 2

HCID 222Ammonia2×HCID 545112118-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester

Produkt 1

HCID 212714728-Hydroxy-2-methyl-7-quinolinecarboxamide

Versuchsvorschrift

8-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.

Aufarbeitung

  1. customto evaporate
  2. customthe residue is crystallized from a suitable solvent

Quellen und Nachweise

ORD-Eintrag
ord-ef05399eb9df4057bf5a42e992a8dd63
Quelldatensatz
uspto-grants-1987_11
Patentnummer
US04705853

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