Ammonia → 6-Hydroxyquinoline-5-carboxamide
Reaktionsgleichung
C[O:2][C:3]([C:5]1[C:6]2[CH:7]=[CH:8][CH:9]=[N:10][C:11]=2[CH:12]=[CH:13][C:14]=1[OH:15])=O.[NH3:16]>>[OH:15][C:14]1[CH:13]=[CH:12][C:11]2[N:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]=1[C:3]([NH2:16])=[O:2]Komponenten
3
Versuchsvorschrift
6-Hydroxy-5-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.
Aufarbeitung
- customto evaporate
- customthe residue is crystallized from a suitable solvent
Quellen und Nachweise
- ORD-Eintrag
- ord-6953e0b03bcf4c10b8aacaebd74f0980
- Quelldatensatz
- uspto-grants-1987_11
- Patentnummer
- US04705853
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