Ethyl formate → HCID 178522216, Verbindung

HRID 24759Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 24759
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8]/[C:9](=[C:16]2\[C:17](=[O:25])[NH:18][C:19]3[C:24]\2=[CH:23][CH:22]=[CH:21][CH:20]=3)/[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.[CH:26](OCC)=[O:27]>CN(C=O)C>[CH:26]([NH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8]/[C:9](=[C:16]2\[C:17](=[O:25])[NH:18][C:19]3[C:24]\2=[CH:23][CH:22]=[CH:21][CH:20]=3)/[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][CH:3]=1)=[O:27]

Komponenten

4

Edukt 2

HCID 8025Ethyl formateHCID 178507732HCID 178507732, Verbindung

Produkt 1

HCID 178522216HCID 178522216, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

200 mg (0.6 mmol) of (Z)-3-[1-(4-aminophenylamino)-1-phenyl-methylidene]-2-indolinone and 5 ml of ethyl formate are stirred in 2.5 ml of DMF for 60 hours at 90° C. After removal of the solvent in vacuo ethyl acetate is added and the mixture is again concentrated by evaporation. The residue is stirred with ether, suction filtered and dried.

Aufarbeitung

  1. customAfter removal of the solvent in vacuo ethyl acetate
  2. additionis added
  3. concentrationthe mixture is again concentrated by evaporation
  4. filtrationfiltered
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-84077a15d7984efd82434c9bbf6b0b42
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06855710B2

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