Reaktionsgleichung
[CH2:1]([OH:12])[C@H:2]([C@H:4]([C@@H:6]([C@@H:8]([CH2:10][OH:11])[OH:9])[OH:7])[OH:5])[OH:3].[CH3:13][C:14]([CH3:16])=O>>[CH3:13][C:14]1([CH3:16])[O:9][CH:8]([CH:6]2[O:7][C:2]([CH3:4])([CH3:1])[O:5][CH:4]2[CH:2]2[O:3][C:8]([CH3:10])([CH3:6])[O:12][CH2:1]2)[CH2:10][O:11]1Komponenten
3
Versuchsvorschrift
1,2:3,4:5,6-Tri-o-isopropylidene-d-mannitol is prepared by rapidly stirring with a mechanical stirrer, of 40 g of mannitol and 500 ml of anhydrous acetone in the presence of 4.0 ml of concentrated (18M) sulfuric acid as a catalyst for 24 hours in a 2 liter flask. The sulfuric acid is neutralized with about 6.8 g anhydrous sodium carbonate and the acetone is evaporated by vacuum distillation at about 30° C. The remaining yellowish oil is diluted with an equal volume of cold water in order to provide the crystalline product. The crystals are filtered, dried, and used without further purification.
Aufarbeitung
- concentrationof concentrated (18M) sulfuric acid as a catalyst for 24 hours in a 2 liter flask
- customthe acetone is evaporated by vacuum distillation at about 30° C
- additionThe remaining yellowish oil is diluted with an equal volume of cold water in order
- customto provide the crystalline product
- filtrationThe crystals are filtered
- customdried
- customused without further purification
Quellen und Nachweise
- ORD-Eintrag
- ord-5e48a3d4b11b49e5841c760cbf362875
- Quelldatensatz
- uspto-grants-1987_11
- Patentnummer
- US04709059
Verknüpfte Notizen
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