Sodium Hydroxide → 3-Phenoxybenzyl alcohol

HRID 247724

Reaktionsgleichung

Reaktionsgleichung von HRID 247724
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=1)(=O)C.[OH-].[Na+]>CO>[O:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH2:5][OH:4])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 170904Benzenemethanol, 3-phenoxy-, 1-acetate

Produkt 1

HCID 262953-Phenoxybenzyl alcoholAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N sodium hydroxide solution are refluxed for three hours. Then the methanol is distilled off and the organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of 1N hydrochloric acid solution and 10 cm3. of water. 1.90 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 95%.

Aufarbeitung

  1. distillationThen the methanol is distilled off
  2. dissolutionthe organic phase is dissolved in 30 cm3
  3. washof methylene chloride, washed with 10 cm3

Quellen und Nachweise

ORD-Eintrag
ord-1a6f3bb1de714fc18ae39f93cc964184
Quelldatensatz
uspto-grants-1987_11
Patentnummer
US04709081

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