Hydrochloric Acid → HCID 11780934, Verbindung

HRID 247845Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 247845
[CH3:1][N:2]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=2)[CH2:8][CH2:7]1)C(=O)C.Cl>CO>[F:23][C:20]1[CH:19]=[CH:18][C:17]([O:16][CH2:15][CH2:14][CH2:13][CH2:12][N:9]2[CH2:8][CH2:7][CH:6]([NH:2][CH3:1])[CH2:11][CH2:10]2)=[CH:22][CH:21]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 19764643N-Methyl-N-{1-[4-(p-fluorophenoxy)butyl]-4-piperidyl}acetamide

Produkt 1

HCID 11780934HCID 11780934, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

0.05 mole of the compound obtained in stage D is refluxed for 12 hours in the presence of 570 cm3 of methanol and 340 cm3 of 5N hydrochloric acid. The methanol is evaporated and the mixture is poured into ice and then basified with sodium hydroxide. It is extracted with ether.

Aufarbeitung

  1. customThe methanol is evaporated
  2. additionthe mixture is poured into ice
  3. extractionIt is extracted with ether

Quellen und Nachweise

ORD-Eintrag
ord-c01548b052cb476bb7336025740cb417
Quelldatensatz
uspto-grants-1993_05
Patentnummer
US05208243

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