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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 247848Erstellt: 25. Oktober 2026

Chloroethane → N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide dihydrochloride

https://huagongshe.com/reaction/247848

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktChloroethaneHCID 6337—
EduktN-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamideHCID 9890945—
LösungsmittelAcetonitrileHCID 6342—
ProduktN-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide dihydrochlorideHCID 19764599—

Reaktionsschritte

5.5 g of the compound obtained in stage A is taken up in 10 cm3 of acetonitrile. 7.5 cm3 of a 3.3N solution of hydrochloric ether are added to this solution. 3.1 g of a solid which corresponds to the title compound are obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05208243
Quelldatensatzuspto-grants-1993_05
ORD IDord-5e7f19ff56af4ccabb05d3f49423a133
Quellennotizuspto-grants-1993_05