4-(3-Mercaptophenyl)-4-methoxytetrahydropyran → 4-Methoxy-4-[3-(1,1,3,3-tetramethyl-2,2-dioxo-1,3-dihydrobenzo[c]thien-5-ylthio)phenyl]tetrahydropyran
Reaktionsgleichung
I[C:2]1[CH:16]=[CH:15][C:5]2[C:6]([CH3:14])([CH3:13])[S:7](=[O:12])(=[O:11])[C:8]([CH3:10])([CH3:9])[C:4]=2[CH:3]=1.[SH:17][C:18]1[CH:19]=[C:20]([C:24]2([O:30][CH3:31])[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)[CH:21]=[CH:22][CH:23]=1>>[CH3:31][O:30][C:24]1([C:20]2[CH:21]=[CH:22][CH:23]=[C:18]([S:17][C:2]3[CH:16]=[CH:15][C:5]4[C:6]([CH3:14])([CH3:13])[S:7](=[O:12])(=[O:11])[C:8]([CH3:10])([CH3:9])[C:4]=4[CH:3]=3)[CH:19]=2)[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1Komponenten
3
Versuchsvorschrift
Using a similar procedure to that described in Example 12, 5-iodo-1,1,3,3-tetramethyl-1,3-dihydrobenzo[c]thiophene-2,2-dioxide was reacted with 4-(3-mercaptophenyl)-4-methoxytetrahydropyran to give 4-methoxy-4-[3-(1,1,3,3-tetramethyl-2,2-dioxo-1,3-dihydrobenzo[c]thien-5-ylthio)phenyl]tetrahydropyran in 28% yield, m.p. 133°-135° C.