HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → (3Z)-3-[[4-(morpholin-4-ylmethyl)anilino]-phenylmethylidene]-5-nitro-1H-indol-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 4-(Morpholinomethyl)aniline | HCID 776851 | — |
| Edukt | 1-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone | HCID 54280104 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | (3Z)-3-[[4-(morpholin-4-ylmethyl)anilino]-phenylmethylidene]-5-nitro-1H-indol-2-one | HCID 178517274 | — |
Reaktionsschritte
Prepared analogously to Example 82 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-morpholinomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06855710B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-b5062f56dc5e453b9cebe08f1cbeadce |
| Quellennotiz | uspto-grants-2005_02 |