HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluoroquinolonic acid → 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(phenoxymethyl)-1-piperazinyl]-3-quinolinecarboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Fluoroquinolonic acid | HCID 483180 | — |
| Edukt | 3-Phenoxymethylpiperazine | HCID 19763604 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(phenoxymethyl)-1-piperazinyl]-3-quinolinecarboxylic acid | HCID 14839407 | — |
Reaktionsschritte
A 0.6 g portion of 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1.23 g of 3-(phenoxymethyl)piperazine and 5 ml of pyridine were reacted as described in Example 81, giving 235 mg of the desired product, mp 112°-115° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05210193 |
| Quelldatensatz | uspto-grants-1993_05 |
| ORD ID | ord-60bd551670914408ab036a718445de43 |
| Quellennotiz | uspto-grants-1993_05 |