4-Methylmorpholine → Glycine,n-(1-oxo-3-phenyl-2-propen-1-yl)-, methyl ester

Beteiligte Stoffe

Reaktionsschritte

Cinnamic acid (38.0 g) was coupled to glycine methyl ester hydrochloride in dimethylformamide by treatment with dicyclohexylcarbodiimide (52.84 g) and 1-hydroxybenzotriazole (39.24 g), followed by N-methylmorpholine (37.56 ml). The reaction mixture was stirred overnight at room temperature and then worked up in the usual manner to give the desired product.

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