Methyl Acrylate → Methyl 3-[(2-thienylmethyl)thio]propanoate

HRID 248828

Reaktionsgleichung

Reaktionsgleichung von HRID 248828
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][SH:7].[CH3:8][O:9][C:10](=[O:13])[CH:11]=[CH2:12].N1CCCCC1.[OH-].C([N+](C)(C)C)C1C=CC=CC=1>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][S:7][CH2:12][CH2:11][C:10]([O:9][CH3:8])=[O:13]

Komponenten

5

Edukt 4

HCID 7294Methyl AcrylateHCID 8082PiperidineHCID 66854Benzyltrimethylammonium hydroxideHCID 80408Thenyl mercaptan

Produkt 1

HCID 15225387Methyl 3-[(2-thienylmethyl)thio]propanoate

Versuchsvorschrift

A solution of 2-thiophenemethanethiol (12 grams), methylacrylate (7.94 grams), piperidine (3 mL) and N-benzyltrimethylammonium hydroxide (3 mL) was stirred for 16 hours at room temperature. The reaction mixture was distilled in vacuo to yield the desired title compound. Yield: 16.5 grams (83%). Bp: 140° C. at 1 mmHg.

Aufarbeitung

  1. distillationThe reaction mixture was distilled in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-9c6e7bf39f6f4949ae051db4b2cfae12
Quelldatensatz
uspto-grants-1993_05
Patentnummer
US05212169

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