HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
methyl D-alaninate → (R)-2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | methyl D-alaninate | HCID 89020 | — |
| Edukt | 1-Chloro-4-hydroxyisoquinoline-3-carboxylic acid | HCID 11020520 | — |
| Produkt | (R)-2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester | HCID 86595457 | — |
Reaktionsschritte
1-Chloro-4-hydroxy-isoquinoline-3-carboxylic acid, 0.55 g, was coupled with 0.40 g of D-Alanine methyl ester analogously to Example A-54 a) and 0.200 g of off-white, solid product were obtained: MS-(+)-icon, M+1=308.8 amu.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07863292B2 |
| Quelldatensatz | uspto-grants-2011_01 |
| ORD ID | ord-1d5fbf3a85b94c949f62768bb560fd42 |
| Quellennotiz | uspto-grants-2011_01 |