HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl D-alaninate hydrochloride → (R)-2-[(7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl D-alaninate hydrochloride | HCID 11182647 | — |
| Edukt | 1-Chloro-4-hydroxy-7-isopropoxy-isoquinoline-3-carboxylic acid | HCID 53870439 | — |
| Produkt | (R)-2-[(7-Isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]propionic acid | HCID 86595460 | — |
Reaktionsschritte
Analogously to Example A-56, 0.040 g of 7-isopropoxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid were allowed to react with D-Alanine methyl ester hydrochloride. The intermediate ester product was hydrolyzed as in Example A-56 to give 0.042 g of a white solid: MS-(−)-ion, M−1=353.0 amu.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07863292B2 |
| Quelldatensatz | uspto-grants-2011_01 |
| ORD ID | ord-29e4ce0491cf45cca2f91a7175ab0542 |
| Quellennotiz | uspto-grants-2011_01 |