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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 251760Erstellt: 26. Oktober 2026

p-Bromoacetophenone → 2-(4-Bromophenyl)quinoline

https://huagongshe.com/reaction/251760

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Eduktp-BromoacetophenoneHCID 7466—
EduktSodium HydroxideHCID 14798—
Edukt2-AminobenzophenoneHCID 76080—
LösungsmittelEthanolHCID 702—
Produkt2-(4-Bromophenyl)quinolineHCID 147344478,3%

Reaktionsschritte

Dissolving 5.0 g (25 mmol) of 4-bromoacetophenone and 5.0 g (25 mmol) of 2-aminobenzophenon into 50 milliliter of ethanol, adding 3.1 g of sodium hydroxide, the resultant suspension was refluxed under heating for 7 hours. After completion of the reaction, separation with filtration was carried out and resultant crystals were washed with water and ethanol, thereby obtaining 5.56 g of 2-(4-bromo-phenyl)-quinoline (yield: 61%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07867629B2
Quelldatensatzuspto-grants-2011_01
ORD IDord-c554a8b419c44fce967ba6f31283fd67
Quellennotizuspto-grants-2011_01