HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
p-Bromoacetophenone → 2-(4-Bromophenyl)quinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | p-Bromoacetophenone | HCID 7466 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 2-Aminobenzophenone | HCID 76080 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-(4-Bromophenyl)quinoline | HCID 1473444 | 78,3% |
Reaktionsschritte
Dissolving 5.0 g (25 mmol) of 4-bromoacetophenone and 5.0 g (25 mmol) of 2-aminobenzophenon into 50 milliliter of ethanol, adding 3.1 g of sodium hydroxide, the resultant suspension was refluxed under heating for 7 hours. After completion of the reaction, separation with filtration was carried out and resultant crystals were washed with water and ethanol, thereby obtaining 5.56 g of 2-(4-bromo-phenyl)-quinoline (yield: 61%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07867629B2 |
| Quelldatensatz | uspto-grants-2011_01 |
| ORD ID | ord-c554a8b419c44fce967ba6f31283fd67 |
| Quellennotiz | uspto-grants-2011_01 |