6-Amino-3-chloropyridazine → 3-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile

Beteiligte Stoffe

Reaktionsschritte

1 mmol 3-(2-bromoacetyl)benzonitrile and 1 mmol 6-chloropyridazin-3-amine in 10 ml EtOH were heated to reflux for 12 h, then cooled to room temperature. The orange-red precipitate was collected by filtration, washed with cold EtOH, and air-dried to give the 3-(6-chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile (125 mg, 50%).

Herkunft & Nachweise