HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ether hydrochloride → N-{2-[4-{4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ether hydrochloride | HCID 10953452 | — |
| Edukt | N-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide | HCID 86752291 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | N-{2-[4-{4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide hydrochloride | HCID 86752292 | 99,8% |
Reaktionsschritte
N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide (65 mg, 0.12 mmol) was dissolved in methylene chloride (2 ml) to which was subsequently added saturated hydrogen chloride/ether solution (1 ml). After 5 minutes of stirring, the solvent was removed by evaporation, and the resulting residue was solidified in ether (5 ml) and collected by filtration to obtain 69 mg (99.8%) of the title compound in a colorless amorphous powder form.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05728835 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-e047a94edb4343a0b2070338fbae9a7f |
| Quellennotiz | uspto-grants-1998_03 |