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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2521Erstellt: 25. Oktober 2026

Ether hydrochloride → N-{2-[4-{4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide hydrochloride

https://huagongshe.com/reaction/2521

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEther hydrochlorideHCID 10953452—
EduktN-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamideHCID 86752291—
LösungsmittelDichloromethaneHCID 6344—
ProduktN-{2-[4-{4-Fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide hydrochlorideHCID 8675229299,8%

Reaktionsschritte

N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-4-(N-hydroxyimino)-N-(2-methoxyphenyl)benzenesulfonamide (65 mg, 0.12 mmol) was dissolved in methylene chloride (2 ml) to which was subsequently added saturated hydrogen chloride/ether solution (1 ml). After 5 minutes of stirring, the solvent was removed by evaporation, and the resulting residue was solidified in ether (5 ml) and collected by filtration to obtain 69 mg (99.8%) of the title compound in a colorless amorphous powder form.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05728835
Quelldatensatzuspto-grants-1998_03
ORD IDord-e047a94edb4343a0b2070338fbae9a7f
Quellennotizuspto-grants-1998_03