P-Toluenesulfonamide → N-tosyliminophenyliodinane

HRID 252222

Reaktionsgleichung

Reaktionsgleichung von HRID 252222
C(O[C:5]1[C:6](OC(=O)C)=[C:7]([I:11])[CH:8]=[CH:9][CH:10]=1)(=O)C.[OH-].[K+].[CH3:18][C:19]1[CH:20]=[CH:21][C:22]([S:25]([NH2:28])(=[O:27])=[O:26])=[CH:23][CH:24]=1>CO>[C:19]1([CH3:18])[CH:20]=[CH:21][C:22]([S:25]([N:28]=[C:7]2[CH2:6][CH2:5][CH2:10][CH2:9][I:11]2[C:7]2[CH:6]=[CH:5][CH:10]=[CH:9][CH:8]=2)(=[O:27])=[O:26])=[CH:23][CH:24]=1

Komponenten

5

Edukt 3

HCID 6269P-ToluenesulfonamideHCID 14797Potassium HydroxideHCID 21865429Bis(acetoxy)iodobenzene

Produkt 1

HCID 86611515N-tosyliminophenyliodinaneAusbeute 113,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Diacetoxyiodobenzene (12.88 g, 40 mmol) was added to a solution of KOH (5.61 g, 100 mmol) and p-toluenesulfonamide (6.85 g, 40 mmol) in methanol (160 mL) at 8° C. A yellow color developed within 1 minute. The cooling bath was removed, and the solution was allowed to warm to RT with stirring for 3 hours. Water (180 mL) was added and the reaction was refrigerated overnight. The precipitate was collected by filtration and dried overnight in a vacuum dessicator to yield 10 g (66%) of a light yellow solid which was used with out further purification or characterization.

Aufarbeitung

  1. customThe cooling bath was removed
  2. additionWater (180 mL) was added
  3. waitthe reaction was refrigerated overnight
  4. filtrationThe precipitate was collected by filtration
  5. customdried overnight in a vacuum dessicator

Quellen und Nachweise

ORD-Eintrag
ord-d3bd792dcf0f4539a355ce4befb7d585
Quelldatensatz
uspto-grants-2011_01
Patentnummer
US07868023B2

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