HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ammonium formate → 4-Fluoro-2-(4-methyl-1H-imidazol-1-yl)aniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ammonium formate | HCID 2723923 | — |
| Edukt | 1-(5-Fluoro-2-nitrophenyl)-4-methyl-1H-imidazole | HCID 57732447 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | 4-Fluoro-2-(4-methyl-1H-imidazol-1-yl)aniline | HCID 57732445 | 104,9% |
Reaktionsschritte
Reaction of intermediate 1A (20.2 g, 91.4 mmol), 10% Pd/C (5.0 g, 4.57 mmol), and ammonium formate (34.7 g, 502.7 mmol) provided the product 2A as an off-white solid (18.34 g, 99% yield). EIMS 192.0 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07875618B2 |
| Quelldatensatz | uspto-grants-2011_01 |
| ORD ID | ord-3b84d77112544adc8a0e93735b9ffb66 |
| Quellennotiz | uspto-grants-2011_01 |